February 2024 SOCRA Source Journal - Journal - Page 28
TABLE 3:
BENEFITS OF CLINICAL TRIAL REGISTRATION AND RESULTS REPORTING7
Registry purposes:
• Fulfill ethical obligations to participants and the research community
◦ Groups that benefit:
▪ Patients
▪ General public
▪ Research community
• Provide information to potential participants and referring clinicians
◦ Groups that benefit:
▪ Patients
▪ Clinicians
• Reduce publication bias
◦ Group that benefits:
▪ Users of the medical literature
• Help editors and others understand the context of study results:
◦ Groups that benefit:
▪ Journal editors
▪ Users of the medical literature
• Promote more efficient allocation of research funds:
◦ Groups that benefit:
▪ Granting agencies
▪ Research community
• Help institutional review boards (IRBs) determine the appropriateness of a research study
◦ Groups that benefit:
▪ IRBs
▪ Ethicists
Results database purposes:
• Provide a public record of basic study results in a standardized format
◦ Groups that benefit:
▪ Researchers
▪ Journal editors
▪ IRBs
▪ Ethicists
• Promote the fulfillment of ethical obligations to participants and the overall contribution of research results
to medical knowledge:
◦ Groups that benefit:
▪ Patients
▪ General public
▪ Research community
• Reduce publication and outcome reporting biases
◦ Group that benefits:
▪ Users of the medical literature
• Facilitate systematic reviews and other analyses of the research literature
◦ Groups that benefit:
▪ Researchers
▪ Policymakers
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SOCRA SOURCE © May 2023