Research & Innovation 2015-16 - Page 120



Feature
Scientists uncover the genomic
blueprint of bat-wing development
Linked studies identify gene regulatory switches that turn bat genes on
and off at crucial times during limb development, with implications for
understanding how differences in the size, shape and structure of limbs are
generated in mammals in general, including humans.
An international team of scientists from the University of
Cape Town (UCT) and the University of California, San
Francisco (UCSF) has, for the first time, identified both
genes and gene regulatory elements that are essential
in wing development in the Natal long-fingered bat
(Miniopterus natalensis), a species widely distributed in
east and southern Africa.
115 UCT RESEARCH & INNOVATION 2015–16





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