IDRR APRIL -MAY -JUNE 2020 - Flipbook - Page 65
INTERDISCIPLINARY
gingival sulcus. The current literature reveals that
contrary to what occurs in the GI tract, initiation of
oral infectious diseases and disease status are
associated with increased diversity and richness of
the microbiota. Oral health is associated with low
diversity and richness within the microbial community.
This review also highlights the host response to the oral
microbiomes in specific niches by consideration of
the immunopathogenesis of periodontal disease and
the immune defenses against caries.
Dental caries is most prevalent disease in the world.
W.D.Miller & his contemporaries gave us our first real
understanding of dental caries process more than
100 years ago. They demonstrated that dental caries
was a bacterially mediated process. Today we know
that dental caries is a multifaceted disease process.
Several models have been useful to elucidate the
mechanism in play. One of the earlier models that is
familiar to most dentists was put forth by Fitzgerald
and Keyes. Overlapping rules describing the host,
bacteria & nutrients required to foment the production
of organic acids & the subsequent demineralization
activity & the beauty of this model is that all three
elements must be present for the disease to progress.
Since all the 3 are required for disease imitation &
progression, removal of any one element leads to the
interception of the disease process. To overcome the
limitations of the traditional disease management
strategies, a number of researchers are developing
‘PROBIOTIC’ methods to treat the caries.
based on scientific databases from COCHRANE
collaboration having a definite RCT (Randomised
Control Trial), a relationship between dental caries,
periodontal disease and intestinal flora.
A systematic review of the above mentioned modalities
including the above mentioned parameters was
carried out and correlation amongst the three
documented in order to demonstrate the title of the
study.
During this 22 Randomised control trial based studies
were done out of which finally 17 articles were
chosen which approved the criterion for systematic
Review
RESULT AND CONCLUSION
AIM OF THE STUDY:
To evaluate and assess the relationship between
dental caries, periodontal diseases and Intestinal flora
RESEARCH QUESTION:
Is there actually any relationship between dental
caries, periodontal disease and internal flora? If yes,
what is its significance?
MATERIALS AND METHODS
Study sample included review of research articles,
July-August-September 2019
The actual need for this systematic review was laid on
the foundation of following conclusions which were
drawn from the final 17 studies that were finally
selected after having undergone the inclusion and
exclusion criterion.70-75% of the studies give a positive
relationship between the 3 entities.25-30% of the
studies give a negative relationship.
This systematic review conducted in order to
document the significance of the relationship
between the intestinal flora, dental caries and
periodontal diseases was found to be highly significant.
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