eResearch Report 2017 - 2018 - Page 32



Supporting the research endeavour
Needle in a
haystack: Wrangling
data to identify host
biomarkers of TB
progression
Up to 80% of the adult
South African population is
estimated to be infected with
Mycobacterium tuberculosis
(Mtb), the bacterium that
causes tuberculosis (TB).
However, about 90% of
healthy individuals believed
to be carriers of the bacteria
will never get sick or infect
anyone else. If researchers
could pinpoint what causes
TB to progress in some
individuals and not in others,
they could break the back of
the TB epidemic.
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